Innovative Medicine of Kuban #4 (2018)

InnovativeMedicineofKuban #4(2018)

CONTENTS

Original articles

Issue of neurological complications risk after surgery for posttraumatic deformity of lumbar and thoracic spine

A.A. Afaunov 1, A.V. Kuzmenko 2, I.V. Basankin 2, M.Yu. Ageev 1

1 Kuban State Medical University, Krasnodar, Russia

2 Scientific Research Institute – Ochapovsky Regional Clinical Hospital #1, Krasnodar, Russia

Surgical correction and stabilization in post-traumatic spinal deformities is associated with the risk of neurological complications. However, at the present time, there are no prognostic scales for assessing the risk of neurological complications of surgical treatment of this category of patients.

Aim: to offer a rapid assessment system for the risk of neurological complications in the surgical treatment of patients with posttraumatic deformities of the thoracic and lumbar spine.

Materials and methodsThe results of treatment were analyzed in 124 patients with post-traumatic deformities of the thoracic and lumbar spine for the period 2003-2017. Among them, 70 men and 54 women aged from 18 to 54 years. Operations are performed in terms from 6 months to 14 years. since the injury. At the same time, in 61 cases of deformity development was the result of diagnostic errors and / or ineffective conservative treatment. 63 cases - were the result of unsuccessful surgical treatment

ResultsAnalysis of clinical material allowed us to identify 3 factors that determine the possibility of the occurrence of neurological complications of surgical treatment. These are the functional state of the spinal cord and roots in the late post-traumatic period, the spondylometric characteristic of the post-traumatic stenosis of the spinal canal and the localization of the deformity of the spinal column. For each of these factors, several gradations were suggested according to their degree of expression. All possible combinations of various gradations of three of these factors give a total of 46 estimated risk options for the development of neurological complications of surgical treatment of post-traumatic deformities of the thoracic and lumbar spine.

ConclusionThe proposed scale can be the basis for express assessment of the risk of neurological complications in the surgical treatment of patients with posttraumatic deformities of the thoracic and lumbar spine.

Key words: spine, complications, post-traumatic deformity, classification, neurological deficit, scale.

Author Credentials

Afaunov A.A., PhD, head of the traumatology and orthopaedics department and BFS, Kuban State Medical University (Krasnodar, Russia). E-mail: afaunovkr@

mail.ru.

Kuzmenko A.V., CMS, neurosurgeon,neurosurgery department #3,

Scientific Research Institutе - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Basankin I.V., CMS, head of neurosurgery department #3, Scientific Research Institutе - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Ageev M.Yu., assistant of the traumatology and orthopaedics department and BFS, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .



Clinical Researches

Platelet-rich plasma for persistent ulcers of the lower limbs

I.V. Gilevich, T.V. Fedorenko, E.A. Kolomyitseva, V.V. Fedushkin,

E.N. Shubrov, S.G. Slavinsky

Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

Background Estimation of safety and efficiency of platelet-rich plasma in complex treatment in patients with persistent large ulcers.

Materials and methods Two clinical cases of patients with long persistent ulcers of the lower extremities that were administered local injections of the autologic platelet-rich plasma in the wound area in combination with or without autodermoplasty.

Results In the first case the patient had a trophic ulcer after erysipelatous inflammation without dynamics to healing in the setting of the carried treatment. Surgery was contraindicated due to severe accompanying pathology. This patient had 6 PRP courses (once a week). The regional epithelialization appeared on the 2nd week. After 6 injections full wound healing was noted. In the second case the patient had is a long persistent post-traumatic ulcer with 2% - square. The autodermoplasty with local introduction of PRP was performed. We observed a full graft acceptance on the 6th day.

Conclusion PRP use will allow to improve outcomes of treatment persistent ulcers of the lower extremities. It represents extremely important to continue work on PRP application due to an absence of complications and obvious contraindications in this method for carrying out comprehensive analysis.

Key words: platelet-rich plasma, long persistent ulcers of the lower limbs.

Author Credentials

Gilevich I.V., PhD, head of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Fedorenko T.V., biologist of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Kolomiytceva E.A., biologist of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Fedyushkin V.V., surgeon of the department of purulent surgery, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Shubrov E.N., surgeon of the department of purulent surgery, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Slavinskiy V.G., PhD, surgeon of the department of purulent surgery, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .



Case reports

Extracorporal cardiopulmonary resuscitation (ECPR) following pulmonary artery rupture in an infant

I.A. Kornilov, I.A. Soynov, A.V. Zubritsky, Y.Y. Kulyabin, S.M. Ivantsov, A.V. Gorbatykh, N.R. Nichay, A.Y. Omelchenko

Meshalkin National Medical Research Center, Novosibirsk, Russia

The rupture of the pulmonary artery during balloon valvular dilatation is rare and the severest complication. In this clinical case we described the rupture of the pulmonary artery in a 10-month-old baby with cardiac tamponada and an extreme hemodilution due to blood loss. CPR has been using for 40 minutes but being ineffective. For 3 days we have been applying ECMO. This patient was discharged without any neurological disorders.

Key words: ECMO, pulmonary artery rupture, balloon dilatation, extracorporal cardiopulmonary resuscitation, hemorrhage.

Author Credentials

Kornilov I.A., CMS, anesthesiologist- resuscitator, Department of Anesthesiology, senior staff scientist of the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Soynov I.A., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders, senior staff scientist of the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Zubritsky A.V., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders, junior staff scientist the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Kulyabin Y.Y., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders, junior staff scientist the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Ivantsov S.M., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders, staff scientist the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Gorbatykh A.V., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders,junior staff scientist the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Nichay N.R., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders, junior staff scientist the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Omelchenko A.Y., CMS, cardiovascular surgeon, Department of Congenital Heart Disorders, senior staff scientist of the new surgical technologies center, Meshalkin National Medical Research Center (Novosibirsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Endovascular treatment of thepatent ductus arteriosus

A.N. Pakholkov 1, E.S. Suslov 1, K.A. Lashevich 2, A.N. Fedorchenko 1,

V.A. Porhanov 1,2

1 Scientific Research Institution – Ochapovsky Regional Clinical Hospital #1, Krasnodar, Russia

2 Kuban State Medical University, Krasnodar, Russia

Correction of the patent ductus arteriosus (PDA) takes an important place in management of congenital heart defects (CHD). Untreated PDA can lead to heart failure due to left ventricular myocardial hypertrophy (LVH), pulmonary hypertension, bacterial endocarditis, pulmonary infection, and rarely the development of ductal wall aneurysm, its calcification and further rupture.

It is believed that the closure of PDA is indicated in any child or adult who develops pathognomonic symptoms: expansion of the left heart; the presence of signs of pulmonary hypertension with left-right blood discharge; previously transferred endocarditis. In asymptomatic patients with PDA accompanied by left ventricular hypertrophy closure of the duct is indicated to reduce the risk of further complications.

There were various surgical methods of PDA treatment discovered in the period of the development of medical industry. Previously the most common intervention was ligation of the duct, accompanied by thoracotomy. However, in the present days the ligation of PDA is extremely rare. Endovascular occlusion has taken the lead in the modern practice. Its purpose is to close the duct with intravascular access with help of specialised tools.

In this article we present a case of PDA management in a patient with clinical manifestation of PDA at the age of 35 years.

Key words: patent arterial duct, endovascular occlusion, intravascular access.



Author credentials

Pakholkov A.N., surgeon, x-ray diagnosis and treatment department, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Suslov E.S., surgeon, x-ray diagnosis and treatment department, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Lashevich K.A., Resident of department for cardiac surgery and cardiology department FAT, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .



Fedorchenko A.N., PhD, head of the x-ray endovascular diagnostics and treatment department, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Porhanov V.A., PhD, professor, academician of the RAS, chief doctor of Scientific Research Institutе - Ochapovsky Regional Clinic Hospital #1, head of the Department of Oncology with the course of thoracic surgery FPK and PPS, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Donor Wound Treatment with Cell Technologies Application and Vacuum Therapy

A.V. Polyakov 1,2*, S.B. Bogdanov 1,2, D.N. Marchenko 1, I.V. Gilevich 1,2,

T.V. Fedorenko 1

Scientific Research Institution – Ochapovsky Regional Clinical Hospital #1, Krasnodar, Russia


We presented a clinical case of a patient treated for facial burns. We performed full thickness skin grafting taken from the abdominal surface. For treatment of abdominal wound we used dermal autologous fibroblasts, performed free skin grafting with split-skin grafts, and then placed a vacuum closure. A sufficient result was achieved.

Key words:skin grafting, dermal fibroblasts, vacuum therapy.

Author Credentials

Polyakov A.V., CMS, burn surgeon, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, associated professor of general surgery department, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Bogdanov S.B., PhD, head of the burns center, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, professor of the Department of Orthopedics, Traumatology and Military Field surgery, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Gilevich I.V., CMS, head of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, teaching assistant of oncology department with course of thoracic surgery, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Fedorenko T.V., biologist of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

CLINICAL CASE OF THE YOUNG PATIENT WITH ISCHEMIC STROKE AND GENETICALLY CAUSED THROMBOPHILIC PREDISPOSITION

Y.A. Bursa, L.V. Timchenko, M.V. Kolodina

Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

We present a clinical case of an ischemic stroke in a young man, 37 years in the setting of severe cardiac pathology (coronary heart disease, repeated myocardial infarctions with a cardiomyopathy and progressing chronic heart failure).

This patient had an orthotopic heart transplantation. In a month we observed an intense violation of cerebral blood circulation, the diagnosis was established: an ischemic stroke in the right carotid pool with formation of the advanced area of ischemia in the right fronto- temporal and subcortical area. Total condition was complicated with cerebral edema and dislocation syndrome.

In the course of diagnostic search this patient demonstrated genetically caused thrombophilic predisposition in the form of gene- mutation of the blood coagulating factor – plasminogen activator inhibitor (PAI - 1), a glycoprotein Ia (ITAG 2 a heterozygote), F 7 heterozygote; the genetic polymorphism associated with violation of a folate cycle - MTHFR 1298 a heterozygote, the MTR heterozygote. The revealed mutations in heterozygous state genes with predisposition to thrombophilic complications can serve as a background for disorders in anti-coagulation and coagulation system which can appear at identification the factors starting the mechanism of its development. In a case with this patient, we speak about a secondary thrombophilia as a reason of an ischemic stroke in the setting of cardiac pathology, repeated myocardial infarctions, orthotopic heart transplantation, obesity. All above-mentioned factors allowed to administer reasonable pathogenetically justified antiagregant and anticoagulant therapy, folic acid drugs, group B vitamins for a purpose of secondary prevention of thrombotic complications.

Key words: ischemic stroke, orthotopic cardiac transplantation, genetically caused thrombophilic predisposition, gene-mutation.

Author credentials

Bursa Y.A., neurologist, head of the neurological department for patients with ACVE, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Timchenkо L.V., neurologist, head of the neurological department for patients with ACVE, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Kolodina M.V., CMS, kardiologist of diagnostic center, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Reviews

Entotic sound: diagnostic parallels

E.V. Kolpakova, S.A. Zhade, E.A. Kurinnaya, V.V. Tkachev, G.G. Muzlaev

Scientific Research Institution – Ochapovsky Regional Clinic hospital #1, Cardiac surgery department #2, Krasnodar, Russia

We observed issues of etiology and pathogenesis, differentiatied diagnosis of enttic sound which is one of the frequent otoneurological complaints. Classification of this symptom is described.

Key words: tinnitus, somatosound, diagnostics.

Author Credentials

Kolpakova E.V., surdologist, otolaryngologist, diagnostic center, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Zhade S.A., MSC, neurologist, neurosurgery department 2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Kurinnaya E.A., neurologist, head of diagnostic center, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Tkachev V.V., PhD, head of neurosurgery department 2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Muzlaev G.G., PhD, professor, head of neurological diseases and neurosurgery AT department, Kuban State Medical University, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Orthostatic hypotension. Part 1: definition, classification, natural history

G.A. Golovina, O.N. Zhadan, K.A. Zargaryan, O.A. Kravchenko, N.E. Tripolskaya

Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

Orthostatic hypotension (OH) is an excessive decrease of arterial blood pressure when one takes a vertical position. It represents violation of arterial blood pressure circulation at various states and is not an independent disease. OH is associated with an increased risk of the general mortality, incidence of myocardial infarction and cerebral stroke, falling and syncope. We describe definition, classification, prevalence and natural history of OH in this article.

Key words: orthostatic hypotension, syncope, orthostatic test.

Author credentials

G.A. Golovina, CMS, cardiologist, cardiology department #4,Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia).E-mail: //e.mail.ru/compose/?mailto=mailto% Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. " target="_blank"> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Zhadan O.N., neurologist, head of the neurorehabilitation department, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

K.A. Zargaryan, cardiologist, cardiology department #4,Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia).E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

O.A. Kravchenko, cardiologist, cardiology department #4,Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia).E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

N.E. Tripolskaya, cardiologist, cardiology department #4,Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Scientific events chronicle

VII European School of Thoracic surgery

Paper abstracts, 2018

InnovativeMedicineofKuban #3 (2018)

InnovativeMedicineofKuban #3 (2018)

CONTENTS

Original articles

application of Percutaneous endoscopically assisted gastrostomy in multifunction hospital

A.N. Petrovsky 1, I.V. Vagin 1, S.L. Gobaeva 1*, A.Y. Popov 1,

A.G. Barishev 1,2

1 Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 Krasnodar, Russia

2 Kuban State Medical University, Krasnodar, Russia

Corresponding author: *S.L. Gobaeva, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 1st May str., 167, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Background

Optimization of the process and improved efficiency of the prolonged compulsory enteroalimentation in the patients who require it for more than 4 weeks.

Materials and methods

We analyzed the first experience of percutaneous endoscopically assisted gastrostomy in 32 patients. Patients were treated in the neurosurgical and neurologic department of "Research Scientific Institute – Ochapovsky Regional Clinical Hospital No. 1 " Krasnodar.

Results

Application efficiency of percutaneous endoscopically assisted gastrostomy for prolonged enteral feeding in patients with combined trauma and neurological deficiency was shown. is shown to a gastrostomiya for carrying out a long enteroalimentation at patients with the combined trauma and neurologic deficiency. The greatest number of complications 3 (33,3%) was observed in the group of patients with cranio-cereberal traumas.

Key words: enteral feeding, percutaneous endoscopic gastrostomy, enteral feeding complications.

Author credentials

Petrovsky A.N., CMS, surgeon, surgical department #1, Scientific Research Institution- Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Vagin I.V., surgeon, surgical department #1, Scientific Research Institution- Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Gobaeva S.L.,еndoscopy department #2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Popov A.Y., head of surgical department #1, Scientific Research Institution- Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Baryshev A.G., PhD, assistant professor, head of the surgical department #1 FAT and PPS, Kuban State Medical University, deputy chief physician for surgery, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

HEREDITARY TROMBOPHILIA AND ISCHEMIC STROKE IN YOUNG PEOPLE

P.V. Kataev *, L.V. Timchenko, O.N. Zhadan, D.K. Sichinava

Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

Сorresponding author:* P.V. Kataev, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 1st May street, 167, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

In this article the most widespread hereditary trombophilia in the setting of ischemic stroke etiology in young patients is considered. Own data on prevalence of various options of hereditary trombophilia in 188 patients who were treated in neurologic department for patients with acute disorders of cerebral blood circulation in Scientific Research Institute — Ochapovsky Regional Clinic Hospital #1 are provided.

Key words: trombophilia, ischemic stroke, young age.

Author credentials

Kataev P.V., neurologist, neurological department for patients with ACVE, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Timchenko L.V., neurologist, head of the neurological department for patients with ACVE, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Zhadan O.N., neurologist, head of the neurorehabilitation department, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Sichinava D.K., CMS, neurologist,consulting and diagnostic clinic, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia).

E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Case reports

Cell Therapy Application in Skin Grafting Surgery

S.B. Bogdanov *, I.V. Gilevich, T.V. Fedorenko, E.A. Kolomiytseva,

A.V. Polyakov

Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

Corresponding author: * S.B. Bogdanov, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 140 Rossiyskaya str, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

The clinical case of treatment in a patient with extensive defects of hairy part skin of the head and face is presented. The autoplasty with split skin with one-stage closing of wound defects with a big auto-omentum was performed. For the best adaptation of biological transplants the autologous platelet enriched plasma, and the allogenic frozen dermal fibroblasts were applied. The good esthetic and functional result was received.

Key words: skin grafting, greater omentum, cell therapy, allogenic fibroblasts, platelet enriched plasma.

Author Credentials:

Bogdanov S.B., PhD, head of the burns center, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Gilevich I.V., CMS, head of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Fedorenko T.V., biologist of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Kolomiytceva E.A., biologist of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Polyakov A.V., surgeon head of the burns center, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Clinical case of a successfully treated patient with open severe penetrating craniofacial injury

A.A. Kalinin 1,2*, B.B. Sazhin 1, V.Y. Goloborodko 2, G.Y. Levina 2

Corresponding author: A.A. Kalinin, Irkutsky State Medical University, 664005, Irkutsk, 10 Botkina str., e-mail: //e.mail.ru/compose/?mailto=mailto% Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. " target="_blank"> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

1 Irkutsky State Medical University, Irkutsk, Russia

2 Dorozhnaya Clinical Hospital Irkutsk-PAssazhirsky Station OAO «RZhD», Irkutsk, Russia

In 80% cases, craniofacial injury is followed by the cerebrospinal liquid leak from natural ways. The leading life-threatening states at the same time are infectious complications. Approaches for treating such patients are ambiguous and first of all depend on severity of a patient condition. Results of mini-invasive surgical interventions for penetrating craniocereberal trauma are studied insufficiently. In this article we discuss a clinical example of successful staged surgical treatment in a patient with the open severe craniofascial injury.

This clinical case includes two hospital stays: the first has been connected to the severity of craniofascial injury itself, the second – with its complication (rhinoliquorrhea). Following the offered algorithm of managing patients with this pathology, at primary admission we performed a dynamic assessment of the patient and then conservative treatment was carried out, at the repeated admission surgical treatment was performed: lumboperitoneal shunting.

Primary severity of this injury and staged approach to treatment have allowed to achieve positive clinical dynamics at the stage of mini-invasive surgery and also considerably reduce risks for the patient’s life and carry out full rehabilitation at the shortest possible time.

Key words: open penetrating craniofascial injury, rhinoliquorrhea, lumboperitoneal shunting, minimally invasive surgery.

Author Credentials:

Sazhin B.B., resident of neurosurgery and innovative medicine department, Irkutsky State Medical University (Irkutsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Goloborodko V.Y., head of anesthesiology and resuscitation department #1, Dorozhnaya Clinical Hospital Irkutsk-Passazhirsky Station OAO «RZhD» (Irkutsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Levina G.Y., neurologist of Neurosurgery center, Dorozhnaya Clinical Hospital Irkutsk-Pаssazhirsky Station OAO «RZhD» (Irkutsk, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

complicated diagnosis: retroperitoneal alveococcosis in the guise of ormond’s disease

V.L. Medvedev ¹,2, O.A. Vorobieva ², T.M. Morenets ³, O.N. Ponkina ¹*,

E.A. Terman ¹, V.V. Polegenkiy ¹, N.S. Elistratova ², A.V. Barsuk ¹, L.A. Medvedeva ¹

1 Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 Krasnodar, Russia

2 OOO ‘National Center of Clinical Morphological Diagnosis’, Saint Petersburg, Russia

3          Kuban State Medical University, Krasnodar, Russia

Corresponding author: *O.N. Ponkina, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 167, 1st May str., e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.


Diagnosis of parasitic diseases, in a type of their rarity and diversity, always presents considerable difficulties. Clinical observation of an alveococcosis with invasion in the retroperitoneal space with distribution on mediastinal fat proceeding with progressing retroperitoneal fibrosis with ureteral obstruction and hydronephrosis development, with an aorta lumen stenosis, with formation of SVC syndrome in the absence of changes in other parts of the body, first of all in the liver, in the absence of eosinophilia in the peripheral blood throughout all disease and lack of antibodies to echinococci in the blood serum, twice during observation determined by an immunofermental method is presented in this article.

Key words: alveococcosis, retroperitoneal space, retroperitoneal fibrosis.

Author Credentials

Medvedev V.L., PhD, professor, deputy chief doctor on urology, head of urology and nephrology center, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, chief nontenured urologist and transplantologist of Health Care Ministry Krasnodar Region, head of urology department, Kuban State Мedical University (Krasnodar, Russia). E-mail: //e.mail.ru/compose/?mailto=mailto% Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. " target="_blank"> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Vorobieva O.A., CMS, morbid anatomist, department of morbid anatomy, OOO ‘National Center of Clinical Morphological Diagnosis’ (Saint Petersburg, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Morenets T.M., CMS, associated professor, department of infectious diseases and epidemiology ATF, Kuban State Мedical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Ponkina O.N., CMS, head of pathological anatomy department, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: //e.mail.ru/compose/?mailto=mailto% Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. " target="_blank"> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Terman E.A., forensic surgeon, department of morbid anatomy, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Polegenkiy V.V., urologist, oncological urology department,Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Elistratova N.S., radiologist, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Barsuk A.V., forensic surgeon, department of morbid anatomy, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Medvedeva L.A., head of pathological laboratory, department of morbid anatomy, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: //e.mail.ru/compose/?mailto=mailto% Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. " target="_blank"> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Clinical Case of Two-Stage Treatment of a Newborn with Coarctation and Aortic Arch Hypoplasy

M.V. Boriskov, A.N. Fedorchenko, G.A. Efimochkin, I.A.Tkachenko *,

P.J. Petshakovsky, O.A. Vanin

Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

Corresponding author:* I.A. Tkachenko, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 167, 1st May street, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

In the present article we report a clinical case of successful two-stage treatment for juvenile aortic coarctation with aortic arch dysplasia in a newborn. We demonstrated possible application of balloon angioplasty, as a palliative procedure in children with severe health condition.

Key words: juvenile aortic coarctation, aortic arch hypoplasy, balloon angioplasty.

Author credentials

Tkachenko I.A., surgeon, cardiac surgery department #1, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1(Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Boriskov M.V., CMS, head of cardiac surgery department #1, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Fedorchenko A.N., PhD, head of x-ray diagnosis and treatment department #1, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Efimochkin G.A., surgeon, cardiac surgery department #1, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Petshakovsky P.Y., surgeon, cardiac surgery department #1, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Vanin O.A., surgeon, cardiac surgery department #1, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

clinical case of surgery for false aneurysm of the internal carotid artery after carotid endarterectomy and carotid angioplasty

R.A. Vinogradov 1,2, V.V. Matusevich 2*, A.B. Zakeryaev 1

1 Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

2 Kuban State Medical University, Krasnodar, Russia

Corresponding author: * V.V. Matusevich, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 167, 1st May str., e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

In this article a clinical case of surgical treatment for false aneurysm of extracranial department of an internal carotid artery in a 69-year-old patient after numerous surgical treatment for stenosis atherosclerosis of an internal carotid is described. The diagnostic algorithm consisted of triplex scanning of brachiocephalic arteries, a cerebral angiography and a multispiral computer tomography with intravenous contrast enhancement. This patient underwent carotid endarterectomy in combination with reconstruction of an internal carotid and removal of earlier implanted stent and a synthetic patch were performed. The postoperative period was uneventful. Histological assessment proved that extension of an internal carotid was caused by a false aneurysm. Previous surgery and atherosclerosis were the reasons of aneurysm formation.

Key words: false aneurysm of carotid artery, aneurysms of peripheral arteries, carotid endarterectomy, internal carotid artery reconstruction, carotid angioplasty.

Author credentials

Vinogradov R.А., CMS, head of the vascular surgery department, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, assistant of surgery department №1 ATF, Kuban State Medical University (Krasnodar, Russia). E-mail: //e.mail.ru/compose/?mailto=mailto% Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. " target="_blank"> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Matusevich V.V., resident of cardiac surgery and cardiology department ATF, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Zakeryaev A.B., cardiovascular surgeon, department of vascular surgery, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Coronary artery anomaly. coronary-pulmonary fistula

S.V. Topilina *, E.I. Zyablova, A.M. Namitokov, E.D. Kosmacheva

Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

Corresponding author: *S.V. Topilina, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 167, 1st May str., e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

True coronary and pulmonary fistulas occur quite seldom. Most often this defect is a casual finding at diagnosis of other cardiac diseases. Hemodynamics of this defect is caused by the affected coronary artery shunt into the cardiac chamber or the great vessel. Before introduction in modern diagnosis methods of high-precision ultrasonic devices and cardiac treatment to verify such anomaly as a coronary artery fistula, it was impossible. In our study we present a clinical case with right and left coronary artery fistulas into a pulmonary artery and a left atrium.

Key words: coronary artery anomaly, coronary-pulmonary fistula.

Author Credentials

Topilina S.V., radiologist, Scientific Research Institutе - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Zyablova E.I., head of radiology department, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). Е-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Namitokov A.M., head of cardiology department #2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Kosmachеva E.D., PhD, professor, chief medical officer Scientific Research Institute – Ochapovsky RCH #1, head of therapy department #1, Kuban State Medical University, chief cardiologist of Krasnodar region (Krasnodar, Russia). E-mail: //e.mail.ru/compose?To= Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. "> Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Technological Achievements in Medicine

E.V. Vyskubova 1*, N.V. Soroka 1, O.Y. Solodilova 1, I.A. Shelestova 1,2

Echocardiography features for Bland-White-garland syndrome diagnosis in adults

1 Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

2 Kuban State Medical University, Krasnodar, Russia

Corresponding author: * E.V. Vyskubova, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 167, 1st May str., e-mail: usdhelen Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Bland-White-Garland syndrome (BWFS) is an abnormal arising of the left coronary artery (LCA) from the pulmonary artery trunk (PA), (in English-speaking literature ALCAPA – anomalous left coronary artery arising from the pulmonary artery) and it is rather rare pathology, 0,24-0,45% of cases of all congenital heart diseases. There are infantile and adult types described. In most cases, this anatomic anomaly is found at children or teenage age. We present the observations of patients with the BWGS adult type in this article and analyze possibilities of ECG while diagnosing this rare condition.

Key words: Bland-White-Garland syndrome, adult type, echocardiography, coronarography.

Author Credentials

Vyskubova E.V., ultrasound physician, department of ultrasound diagnosis, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Soroka N.V., ultrasound physician, department of ultrasound diagnosis,Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Solodilova O.Y., ultrasound physician, department of ultrasound diagnosis, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Shelestova I.A., CMS, associate professor, deputy chief physician for polyclinic work, Scientific Research Institute - Ochapovsky Regional Clinic Hospital #1, assistant professor, department of cardiac surgery and cardiology ATF,Kuban State Medical University (Krasnodar, Russia). Е-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Endoscopic Ultrasound Investigation for Neuroendocrine Panreatic Neoplasms Diagnosis

N.S. Ryabin 1*, M.I. Bykov 1,2, A.N. Katrych 1, V.V. Schava 1,2

1 Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

2 Kuban State Medical University, department of surgery #1 for advanced training, Krasnodar, Russia

Контакт* N.S. Ryabin, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 1st May str., 167, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Endoscopic ultrasound diagnosis occupies an important role in neuroendocrine tumor diagnosis. Key indicators for diagnostic efficiency of this method regarding a tumor nosology are presented in the present article. We described results of the authors; investigations on ultrasonography for neuroendocrine tumor differentiated diagnosis. Possible mistakes in diagnosis of existing neuroendocrine tumors and a study algorithm are analyzed during endoscopic ultrasound investigation.

Key words: neuroendocrine tumors, endoscopic ultrasound, fine needle aspiration biopsy.

Author credentials

Ryabin N.S., CMS, endoscopist, Endoscopy department #2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Bykov M.I., PhD, professor of surgery department #1 ATF, Kuban State Medical University (Krasnodar, Russia), head of Endoscopy department #2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Katrich A.N., CMS, head of Ultrasound Diagnostics department, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Shchava V.V., post-graduate student of surgery department #1 ATF, Kuban State Medical University (Krasnodar, Russia), Endoscopy department #2, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Reviews

stromal cells of fat tissue for regenerative surgery

V.B. Karpuk 1*, V.A. Porhanov 1,2, M.D. Perova 2, I.V. Gilevich 1

1 Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, Krasnodar, Russia

2 Kuban State Medical University, Krasnodar, Russia

Corresponding author:* V.B. Karpiuk, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1, 350086, Krasnodar, 1st May street, 167, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Background Generalize modern data on the current opportunities and the perspective application directions of stem / stromal cells of fat tissue in regenerative surgery.

Results Preclinical and clinical developments of cellular transplantology techniques and tissue engineering with use of the cultivated multipotent mesenchymal stromal cells of fat tissue and freshly isolated stromal vascular fraction of fat tissue in plastic surgery, maxillofacial surgery, orthopedics, neurosurgery, coloproctology, urology, thoracic surgery, cardiac surgery are presented.

Conclusion Transplantation of stromal vascular fraction of fat tissue for which releasing we do not perform cultivation of cells out of a human body is a safe and effective regenerative technology with an application potential in the wide range of surgical areas.

Key words: regenerative surgery, fat tissue, mesenchymal stromal cells, stromal vascular fraction.



Author Credentials:

Karpiuk V. B., CMS, scientific worker of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Porhanov V.A., PhD, professor, academician of the RAS, head doctor of Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia), head of oncology department with thoracic surgery course ATF, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Perova M.D., PhD, professor, head doctor of dental clinic of KSMU (Krasnodar, Russia), professor of department of surgical dentistry and maxillofacial surgery, Kuban State Medical University (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

Gilevich I.V., CMS, head of the laboratory for development and study of new treatment technologies, Scientific Research Institute – Ochapovsky Regional Clinic Hospital #1 (Krasnodar, Russia). E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. .

45-yers jubilee to burn service of Kuban region

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